The Biochemistry stream explores one of three biochemistry projects:
Project 1: Investigates proteoglycan regulation and proteoglycan-targeting therapies in glioblastoma and liver cancer. Students will learn the following techniques: mammalian cell culture, compound evaluation, western blot, ELISA, enzyme activity assays, CRISPR gene editing, clonal expansion, and genomic analysis.
Project 2: Investigates the molecular mechanisms of aging, age-related diseases, and oxidative stress on muscle proteins function and structural dynamics. Students will learn the following techniques: bacterial cell culture, site-directed mutagenesis, recombinant protein expression and purification, enzyme kinetics, protein-protein binding assays, and protein folding and stability experiments.
Project 3: Investigates vitamin A, and the enzymes that activate vitamin A, and how those enzymes are regulated. Students will learn the following techniques: mammalian cell culture, cell differentiation, RNA isolation, reverse transcription, qPCR, western blot, and enzyme activity assay.
