Dr. Goellner's Selected Publications

Delagoutte E., Goellner G.M., Guo J., Baldacci G., McMurray C.T. (2008) Single-stranded DNA-binding protein in vitro eliminates the orientation-dependent impediment to polymerase passage on CAG/CTG repeats. J Biol Chem. 9:283(19):13341-56.

Goellner, G.M. and C. Gorbea. (2007) Proteasome activators, inhibitors and associated proteins. In "The Ubiquitin Proteasome System in the Central Nervous System: From Physiology to Pathology. (Di Napoli M, Wojcik C, eds). Nova Sciences, Inc., ISBN: 1-60021-749-4.

Bett, J.S., Goellner, G.M., Woodman, B., Pratt, G., Rechsteiner, M.C., and G.P. Bates. (2006) Proteasome Impairment does not Contribute to Pathogenesis in R6/2 Huntington's Disease Mice: Exclusion of Proteasome Activator REG as a Therapeutic Target. Hum. Mol. Genetics. 15(1):33-44.

Gorbea, C., Goellner, G.M., Teter, K., Holmes, R.K., and M.C Rechsteiner. (2004) Characterization of mammalian Ecm29, a 26S proteasome-associated protein that localizes to the nucleus and membrane vesicles. J Biol Chem. 279(52):54849-61.

Goellner, G.M. and M.C. Rechsteiner. (2003) Are Huntington's and Polyglutamine Based Ataxia's Proteasomal Storage Diseases? Int. J. Biochem. Cell Biol. 35(5):562-71. Review.

Goellner, G.M*., DeMarco, S.J.*, and E.E. Strehler. (2003) Characterization of PISP, a Novel Single-PDZ Protein That Binds to All Plasma Membrane Ca2+-ATPase b-Splice Variants. Ann. NY Acad. Sci. 986:461-71. *Authors contributed equally.

Usachev, Y.M., Toutenhoofd, S.L., Goellner, G.M., Strehler, E.E. and S.A. Thayer. (2001) Differentiation Induces Upregulation of Plasma Membrane Ca2+-ATPase and Concomitant Increase in Ca2+ Efflux in Human Neuroblastoma Cell Line IMR-32. J. Neurochem. 76:1756-65.

Kovtun IV, Goellner G.M., and C.T. McMurray. (2001) Structural features of trinucleotide repeats associated with DNA expansion. Biochem Cell Biol. 79(3):325-36. Review.

Richard, G.F., Goellner, G.M., McMurray, C.T., and J.E. Haber. (2000) Recombination-induced CAG Trinucleotide Repeat Expansions in Yeast Involve the MRE11-RAD50-XRS2 Complex. EMBO J. 19:2381-90.

Gacy, A.M.*, Goellner G.M.*., Spiro C., Chen X., Gupta G., Bradbury E.M., Dyer R.B., Mikesell, M.J., Yao J.Z., Johnson A.J., Richter A., Melancon S.B., and C.T. McMurray. (1998) GAA Instability in Friedreich's Ataxia Shares a Common, DNA-directed and Intra-allelic Mechanism with Other Trinucleotide Diseases. Mol. Cell. 1:583-593. *Authors contributed equally.

Goellner, G.M., Tester, D., Thibodeau, S.N., Almqvist, E., Goldberg, Y.P., Hayden, M.R., and C.T. McMurray. (1997) Different Mechanisms Underlie DNA Instability in Huntington Disease and Colorectal Cancer. Am. J. Hum. Gen. 60:879-890.

Gacy, A.M., Goellner G.M., Juranic N., Macura S., and C.T. McMurray. (1995) Trinucleotide Repeats That Expand in Human Disease Form Hairpin Structures In Vitro. Cell. 81:533-540.